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Search Drugs@FDA to access more information on pyrimethamine, including additional drug labels and any generic equivalents. FDA Drug Label Sections PRESCRIBING INFORMATION DESCRIPTION DARAPRIM (pyrimethamine) is an antiparasitic compound available in tablet form for oral administration. Each scored tablet contains 25mg pyrimethamine and the inactive ingredients corn and potato starch, lactose, and magnesium stearate. http://crazylandonadams.sunshineboysquartet.com/2017/01/03/after-a-discussion-of-the-symptoms-the-doctor-may-perform-some-tests-and-exams-to-exactly-diagnose-the-cause-and-prescribe-the-appropriate-treatment/Pyrimethamine, known chemically as 5-(4-chlorophenyl)-6-ethyl-2,4-pyrimidinediamine, has the following structural formula: C12H13ClN4 Mol. Wt. 248.71 CLINICAL PHARMACOLOGY Pyrimethamine is well absorbed with peak levels occurring between 2 to 6hours following administration. It is eliminated slowly and has a plasma half-life of approximately 96hours. Pyrimethamine is 87% bound to human plasma proteins. Microbiology: Pyrimethamine is a folic acid antagonist and the rationale for its therapeutic action is based on the differential requirement between host and parasite for nucleic acid precursors involved in growth. This activity is highly selective against plasmodia and Toxoplasma gondii.
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